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Why does liver disease cause low platelets?
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Liver cells or hepatocytes have glucagon receptors. Glucagon can easily target the liver. When glucagon binds to the glucagon receptors it is then converted into individual glucose molecules by liver cell and release them into the bloodstream. This process is known as glycogenolysis. Glucagon afterw....
An increase in the SGOT and SGPT levels is an indication of liver damage. The normal level of 30 for males and 19 for females if it reaches it medical attention is required. SGPT levels in the blood are thus compared with liver damage for example, from viral hepatitis or with compared to the heart f....
Our liver has a tremendous regenerating capacity. So in order for the virus to be successful, it has to elude this destructive power of inflammation and immunity. When the body is attacked by hepatitis virus, liver cells get damage but in the end, the virus is ousted, repairs commence and things are....
Saurabh Rawat
Low platelets count is one of the major symptoms of liver disease.Reduction of platelets which is also known as Thrombocytopenia occurs mainly due to reduced thrombopoietin. Thrombopoietin is actually a glycoprotein hormone generated by the liver & kidney that regulates the creation of platelets.
Historically, thrombocytopenia was thought to arise from the increased pooling of platelets in the enlarged spleen due to portal hypertension. Portal hypertension may cause the spleen to enlarge and retain white blood cells and platelets, reducing the numbers of these cells and platelets in the blood, but spleen enlargement alone was not the only factor for reduction in platelets.Other factors such as Increased destruction of platelets within the spleen, intrasplenic production of autoantibodies, and plasma expansion resulting in hemodilution can also contribute to thrombocytopenia.